The reason why skin samples are taken instead of doing brain biopsy of Parkinsons disease patients is that taking samples is easier and safer for the patients. Moreover this process gives better and accurate results. When the neurons of patients and non patients are taken and compared then researchers come to know the reasons due to which dopamine neurons die.
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Lev hasnow developed a peptide which mimics DJ-1's normal functionthereby protecting dopamine- producing neurons. What's more thepeptide can be easily delivered by daily injections or absorbedinto the skin through an adhesive patch. Based on a short protein derived from DJ-1 itself the peptide hasbeen shown to freeze neurodegeneration in its tracks reducingproblems with mobility and leading to greater protection of neuronsand higher dopamine levels in the brain. Dr. Lev says that thismethod which has been published in a number of journals includingthe Journal of Neural Transmission could be developed as a preventative therapy.
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So in a sense diagnosing Parkinson's disease gets back to the very roots of what doctors are supposed to do. But when there are no corroborative tests available to prove or disprove a diagnosis even the doctor sometimes gets it wrong. Before delving into the challenges of diagnosing Parkinson's disease let's first consider what is known about this condition.
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